IREB2 Antikörper (AA 1-250)
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- Target Alle IREB2 Antikörper anzeigen
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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Bindungsspezifität
- AA 1-250
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IREB2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- MDAPKAGYAF EYLIETLNDS SHKKFFDVSK LGTKYDVLPY SIRVLLEAAV RNCDGFLMKK EDVMNILDWK TKQSNVEVPF FPARVLLQDF TGIPAMVDFA AMREAVKTLG GDPEKVHPAC PTDLTVDHSL QIDFSKCAIQ NAPNPGGGDL QKAGKLSPLK VQPKKLPCRG QTTCRGSCDS GELGRNSGTF SSQIENTPIL CPFHLQPVPE PETVLKNQEV EFGRNRERLQ FFKWSSRVFK NVAVIPPGTG
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human IREB2 (NP_004127.1).
- Isotyp
- IgG
- Top Product
- Discover our top product IREB2 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:20 - 1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
- Andere Bezeichnung
- IREB2 (IREB2 Produkte)
- Hintergrund
- RNA-binding protein that binds to iron-responsive elements (IRES, which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.,IREB2,ACO3,IRP2,IRP2AD,Endocrine & Metabolism,Cardiovascular,Hypoxia,Hypoxia-Regulated,IREB2
- Molekulargewicht
- 37 kDa/105 kDa
- Gen-ID
- 3658
- UniProt
- P48200
- Pathways
- Transition Metal Ion Homeostasis
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