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IRF3 Antikörper (AA 1-260)

Name: IRF3 Antikörper (AA 1-260)
Brand: antibodies-online
SKU: ABIN6142528
Price: 722.37 EUR
Availability: InStock

IRF3 Reaktivität: Human WB, IHC, IF, ChIP Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using IRF3 antibody. (IRF3 Antikörper (AA 1-260))

Immunofluorescence analysis of HeLa cells using IRF3 antibody (ABIN6128099, ABIN6142528, ABIN6142531 and ABIN7101371) at dilution of 1:100 (40x lens). (IRF3 Antikörper (AA 1-260))

Immunohistochemistry of paraffin-embedded human esophageal cancer using IRF3 antibody. (IRF3 Antikörper (AA 1-260))

IHC (p)

Chromatin immunoprecipitation analysis extracts of HCT116 cell line, using IRF3 rabbit polyclonal antibody. (IRF3 Antikörper (AA 1-260))

ChIP

Immunohistochemistry of paraffin-embedded human lung cancer using IRF3 antibody. (IRF3 Antikörper (AA 1-260))

IHC (p)

5 Abbildungen

(1 reference)

Produktnummer ABIN6142528

Datenblatt (PDF)

Target Alle IRF3 Antikörper anzeigen

IRF3 (Interferon Regulatory Factor 3 (IRF3))
Bindungsspezifität
17

15

15

14

13

9

8

7

6

5

4

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-260
Reaktivität
142

92

56

31

18

3

2

2

2

1

1

1

1
Human
Wirt
150

15

2
Kaninchen
Passende Sekundärantikörper
Klonalität
135

32
Polyklonal
Konjugat
88

12

9

8

4

4

4

4

4

4

2

2

2

2

2

2

2

2

2

2

2

2

2
Dieser IRF3 Antikörper ist unkonjugiert
Applikation
119

67

31

29

29

27

19

9

8

8

6

4

3

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

Sequenz

MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALNRKEGL RLAEDRSKDP HDPHKIYEFV NSGVGDFSQP DTSPDTNGGG STSDTQEDIL DELLGNMVLA PLPDPGPPSL AVAPEPCPQP LRSPSLDNPT PFPNLGPSEN PLKRLLVPGE EWEFEVTAFY RGRQVFQQTI SCPEGLRLVG SEVGDRTLPG WPVTLPDPGM SLTDRGVMSY

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Polyclonal Antibodies

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human IRF3 (NP_001184051.1).

Isotyp

IgG

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anti-Interferon Regulatory Factor 3 (IRF3) antibody
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IRF3 Reaktivität: Human WB, ELISA, IF, IP Wirt: Maus Monoclonal 3C8 unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-360) antibody
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anti-Interferon Regulatory Factor 3 (IRF3) (AA 51-150) antibody
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anti-Interferon Regulatory Factor 3 (IRF3) (C-Term) antibody
IRF3 Reaktivität: Human WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (pSer386) antibody
IRF3 Reaktivität: Human, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1268-1341) antibody
IRF3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibody
IRF3 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (pSer385) antibody
IRF3 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,ChIP,1:20 - 1:100

Kommentare

HIGH QUALITY

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Zhong, Wang, Fang, Zhang, Luo, Shang, Ouyang, Ouyang, Chen, Xiao: "Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling." in: PLoS ONE, Vol. 8, Issue 11, pp. e80976, (2013) (PubMed).
Target

IRF3 (Interferon Regulatory Factor 3 (IRF3))

Andere Bezeichnung

IRF3 (IRF3 Produkte)

Synonyme

irf3 antikoerper, IRF3 antikoerper, C920001K05Rik antikoerper, IRF-3 antikoerper, interferon regulatory factor 3 antikoerper, interferon regulatory factor 7 antikoerper, irf3 antikoerper, IRF3 antikoerper, irf-3 antikoerper, Irf3 antikoerper, IRF7 antikoerper

Hintergrund

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,IIAE7,IRF3,Epigenetics & Nuclear Signaling,Transcription Factors,Immunology & Inflammation,Cytokines,Interferons,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,IRF3

Molekulargewicht

12 kDa/16 kDa/33 kDa/47 kDa/49 kDa

Gen-ID

3661

UniProt

Q14653

Pathways

TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades