ITGB3BP Antikörper (AA 1-111)

Produktnummer ABIN6142587

Produktdetails anti-ITGB3BP Antikörper

Target: ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

Bindungsspezifität: AA 1-111

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGB3BP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MPVKRSLKLD GLLEENSFDP SKITRKKSVI TYSPTTGTCQ MSLFASPTSS EEQKHRNGLS NEKRKKLNHP SLTESKESTT KDNDEFMMLL SKVEKLSEEI MEIMQNLSSI Q

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-111 of human ITGB3BP (NP_055103.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ITGB3BP

Target: ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

Andere Bezeichnung: ITGB3BP (ITGB3BP Produkte)

Synonyme: CENP-R antikoerper, CENPR antikoerper, HSU37139 antikoerper, NRIF3 antikoerper, TAP20 antikoerper, 4930471O16Rik antikoerper, AU022583 antikoerper, integrin subunit beta 3 binding protein antikoerper, integrin beta 3 binding protein (beta3-endonexin) antikoerper, ITGB3BP antikoerper, Itgb3bp antikoerper

Hintergrund: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.,ITGB3BP,CENP-R,CENPR,HSU37139,NRIF3,TAP20,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centromere,Cell Adhesion,Cytoskeleton,ITGB3BP

Molekulargewicht: 6 kDa/12 kDa/19 kDa/20 kDa/24 kDa

Gen-ID: 23421

UniProt: Q13352

Pathways: Neurotrophin Signalübertragung