KPNB1 Antikörper (AA 250-350)

Produktnummer ABIN6142997

Produktdetails anti-KPNB1 Antikörper

Target: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Bindungsspezifität: AA 250-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KPNB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: QYMETYMGPA LFAITIEAMK SDIDEVALQG IEFWSNVCDE EMDLAIEASE AAEQGRPPEH TSKFYAKGAL QYLVPILTQT LTKQDENDDD DDWNPCKAAG V

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human KPNB1 (NP_002256.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KPNB1

Target: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Andere Bezeichnung: KPNB1 (KPNB1 Produkte)

Synonyme: Afu1g15720 antikoerper, AO090005001133 antikoerper, imb1 antikoerper, impnb antikoerper, ipo1 antikoerper, ipob antikoerper, ntf97 antikoerper, IMB1 antikoerper, IPO1 antikoerper, IPOB antikoerper, Impnb antikoerper, NTF97 antikoerper, AA409963 antikoerper, importin beta-1 subunit antikoerper, Importin beta-1 subunit antikoerper, karyopherin (importin) beta 1 L homeolog antikoerper, importin beta 1 antikoerper, karyopherin subunit beta 1 antikoerper, karyopherin (importin) beta 1 antikoerper, AFUA_1G15720 antikoerper, AOR_1_1974174 antikoerper, Bm1_57540 antikoerper, PMAA_065830 antikoerper, AFLA_083750 antikoerper, TSTA_085870 antikoerper, BDBG_07509 antikoerper, MCYG_00039 antikoerper, kpnb1.L antikoerper, LOC100533387 antikoerper, KPNB1 antikoerper, Kpnb1 antikoerper

Hintergrund: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene.,KPNB1,IMB1,IPO1,IPOB,Impnb,NTF97,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,KPNB1

Molekulargewicht: 81 kDa/97 kDa

Gen-ID: 3837

UniProt: Q14974

Pathways: Protein targeting to Nucleus