Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

LAMB2 Antikörper (AA 1579-1798)

LAMB2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6143070
  • Target Alle LAMB2 Antikörper anzeigen
    LAMB2 (Laminin, beta 2 (Laminin S) (LAMB2))
    Bindungsspezifität
    • 15
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1579-1798
    Reaktivität
    • 49
    • 18
    • 16
    Human
    Wirt
    • 55
    • 2
    Kaninchen
    Klonalität
    • 55
    • 2
    Polyklonal
    Konjugat
    • 23
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LAMB2 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 22
    • 21
    • 13
    • 13
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    DVRRAEQLLQ DARRARSWAE DEKQKAETVQ AALEEAQRAQ GIAQGAIRGA VADTRDTEQT LYQVQERMAG AERALSSAGE RARQLDALLE ALKLKRAGNS LAASTAEETA GSAQGRAQEA EQLLRGPLGD QYQTVKALAE RKAQGVLAAQ ARAEQLRDEA RDLLQAAQDK LQRLQELEGT YEENERALES KAAQLDGLEA RMRSVLQAIN LQVQIYNTCQ
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1579-1798 of human LAMB2 (NP_002283.3).
    Isotyp
    IgG
    Top Product
    Discover our top product LAMB2 Primärantikörper
  • Applikationshinweise
    WB,1:1000 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    LAMB2 (Laminin, beta 2 (Laminin S) (LAMB2))
    Andere Bezeichnung
    LAMB2 (LAMB2 Produkte)
    Synonyme
    LAMS antikoerper, NPHS5 antikoerper, AW211941 antikoerper, Lamb-2 antikoerper, Lams antikoerper, SLAM antikoerper, lamb1 antikoerper, lams antikoerper, LAMC1 antikoerper, laminin antikoerper, laminin subunit beta 2 antikoerper, laminin, beta 2 antikoerper, laminin subunit beta 2 L homeolog antikoerper, laminin, beta 2 (laminin S) antikoerper, LAMB2 antikoerper, Lamb2 antikoerper, lamb2.L antikoerper
    Hintergrund
    Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma . Some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 2. The beta 2 chain contains the 7 structural domains typical of beta chains of laminin, including the short alpha region. However, unlike beta 1 chain, beta 2 has a more restricted tissue distribution. It is enriched in the basement membrane of muscles at the neuromuscular junctions, kidney glomerulus and vascular smooth muscle. Transgenic mice in which the beta 2 chain gene was inactivated by homologous recombination, showed defects in the maturation of neuromuscular junctions and impairment of glomerular filtration. Alternative splicing involving a non consensus 5' splice site (gc) in the 5' UTR of this gene has been reported. It was suggested that inefficient splicing of this first intron, which does not change the protein sequence, results in a greater abundance of the unspliced form of the transcript than the spliced form.,LAMB2,LAMS,NPHS5,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Neuroscience,Cardiovascular,Angiogenesis,LAMB2
    Molekulargewicht
    195 kDa
    Gen-ID
    3913
    UniProt
    P55268
    Pathways
    Skeletal Muscle Fiber Development
Sie sind hier:
Kundenservice