MANEA Antikörper (AA 30-100)

Produktnummer ABIN6143458

Produktdetails anti-MANEA Antikörper

Target: MANEA (Mannosidase, Endo-alpha (MANEA))

Bindungsspezifität: AA 30-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MANEA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RPNTATFGAP FGLDLLPELH QRTIHLGKNF DFQKSDRINS ETNTKNLKSV EITMKPSKAS ELNLDELPPL N

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human MANEA (NP_078917.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MANEA

Target: MANEA (Mannosidase, Endo-alpha (MANEA))

Andere Bezeichnung: MANEA (MANEA Produkte)

Hintergrund: N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008],MANEA,ENDO,hEndo,MANEA

Molekulargewicht: 53 kDa

Gen-ID: 79694

UniProt: Q5SRI9