MARCO Antikörper (AA 421-520)

Produktnummer ABIN6143559

Produktdetails anti-MARCO Antikörper

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Bindungsspezifität: AA 421-520

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: SVSVRIVGSS NRGRAEVYYS GTWGTICDDE WQNSDAIVFC RMLGYSKGRA LYKVGAGTGQ IWLDNVQCRG TESTLWSCTK NSWGHHDCSH EEDAGVECSV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 421-520 of human MARCO (NP_006761.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MARCO

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Andere Bezeichnung: MARCO (MARCO Produkte)

Hintergrund: The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.,MARCO,SCARA2,SR-A6,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,MARCO

Molekulargewicht: 43 kDa/52 kDa

Gen-ID: 8685

UniProt: Q9UEW3

Pathways: Activation of Innate immune Response