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MCAM Antikörper (AA 447-646)

Name: MCAM Antikörper (AA 447-646)
Brand: antibodies-online
SKU: ABIN6143621
Price: 866.84 EUR
Availability: InStock

MCAM Reaktivität: Human IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated

Immunohistochemistry of paraffin-embedded human lung cancer using CD146/MCAM Rabbit pAb (ABIN6127568, ABIN6143621, ABIN6143622 and ABIN6218100) at dilution of 1:25 (40x lens). (MCAM Antikörper (AA 447-646))

IHC

Immunofluorescence analysis of cells using CD146/MCAM Rabbit pAb (ABIN6127568, ABIN6143621, ABIN6143622 and ABIN6218100) at dilution of 1:50 (40x lens). (MCAM Antikörper (AA 447-646))

Western blot analysis of extracts of various cell lines, using CD146/MCAM antibody (ABIN6127568, ABIN6143621, ABIN6143622 and ABIN6218100) at 1:500 dilution. (MCAM Antikörper (AA 447-646))

Immunohistochemistry of paraffin-embedded human colon carcinoma using CD146/MCAM Rabbit pAb (ABIN6127568, ABIN6143621, ABIN6143622 and ABIN6218100) at dilution of 1:25 (40x lens). (MCAM Antikörper (AA 447-646))

IHC

Immunofluorescence analysis of HeLa cells using CD146/MCAM Rabbit pAb (ABIN6127568, ABIN6143621, ABIN6143622 and ABIN6218100) at dilution of 1:50 (40x lens). (MCAM Antikörper (AA 447-646))

Immunohistochemistry of paraffin-embedded human lung using CD146/MCAM Rabbit pAb (ABIN6127568, ABIN6143621, ABIN6143622 and ABIN6218100) at dilution of 1:25 (40x lens). (MCAM Antikörper (AA 447-646))

IHC

7 Abbildungen

Produktnummer ABIN6143621

Datenblatt (PDF)

Target Alle MCAM Antikörper anzeigen

MCAM (Melanoma Cell Adhesion Molecule (MCAM))
Bindungsspezifität
16

9

7

6

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 447-646
Reaktivität
128

53

47

14

13

8

8

6

5

2
Human
Wirt
90

62

8

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
82

80
Polyklonal
Konjugat
69

13

12

11

6

5

4

4

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MCAM Antikörper ist unkonjugiert
Applikation
81

79

61

37

21

20

14

11

10

5

4

4

3

3

2

1

1

1

1

1
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Sequenz

VLNLSCEASG HPRPTISWNV NGTASEQDQD PQRVLSTLNV LVTPELLETG VECTASNDLG KNTSILFLEL VNLTTLTPDS NTTTGLSTST ASPHTRANST STERKLPEPE SRGVVIVAVI VCILVLAVLG AVLYFLYKKG KLPCRRSGKQ EITLPPSRKS ELVVEVKSDK LPEEMGLLQG SSGDKRAPGD QGEKYIDLRH

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Polyclonal Antibodies

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 447-646 of human CD146/CD146/MCAM (NP_006491.2).

Isotyp

IgG

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Applikationshinweise

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Andere Bezeichnung

MCAM (MCAM Produkte)

Hintergrund

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.,MCAM,CD146,MUC18,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,MCAM

Molekulargewicht

57 kDa/71 kDa

Gen-ID

4162

UniProt

P43121