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MCFD2 Antikörper (AA 27-146)

MCFD2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6143636
  • Target Alle MCFD2 Antikörper anzeigen
    MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
    Bindungsspezifität
    • 15
    • 7
    • 2
    • 1
    AA 27-146
    Reaktivität
    • 25
    • 23
    • 22
    Human
    Wirt
    • 29
    • 11
    Kaninchen
    Klonalität
    • 30
    • 10
    Polyklonal
    Konjugat
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MCFD2 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 15
    • 13
    • 13
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    EEPAASFSQP GSMGLDKNTV HDQEHIMEHL EGVINKPEAE MSPQELQLHY FKMHDYDGNN LLDGLELSTA ITHVHKEEGS EQAPLMSEDE LINIIDGVLR DDDKNNDGYI DYAEFAKSLQ
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 27-146 of human MCFD2 (NP_644808.1).
    Isotyp
    IgG
    Top Product
    Discover our top product MCFD2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
    Andere Bezeichnung
    MCFD2 (MCFD2 Produkte)
    Synonyme
    hm:zeh1186 antikoerper, wu:fc23b10 antikoerper, wu:fd50d08 antikoerper, zgc:103713 antikoerper, zgc:109915 antikoerper, MCFD2 antikoerper, DKFZp469B098 antikoerper, F5F8D antikoerper, F5F8D2 antikoerper, LMAN1IP antikoerper, SDNSF antikoerper, 1810021C21Rik antikoerper, F5f8d antikoerper, Lman1ip antikoerper, Sdnsf antikoerper, multiple coagulation factor deficiency 2 antikoerper, multiple coagulation factor deficiency 2 L homeolog antikoerper, MCFD2 antikoerper, mcfd2 antikoerper, mcfd2.L antikoerper, Mcfd2 antikoerper
    Hintergrund
    This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LMAN1 (lectin mannose binding protein 1, also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D), a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,MCFD2,F5F8D,F5F8D2,LMAN1IP,SDNSF,Signal Transduction,MCFD2
    Molekulargewicht
    10 kDa/14 kDa/16 kDa
    Gen-ID
    90411
    UniProt
    Q8NI22
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