MFN2 Antikörper (AA 687-757)

Produktnummer ABIN6143801

Produktdetails anti-MFN2 Antikörper

Target: MFN2 (Mitofusin 2 (MFN2))

Bindungsspezifität: AA 687-757

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MFN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: QVQQELSGTF AHLCQQVDIT RDNLEQEIAA MNKKVEALDS LQSRAKLLRN KAGWLDSELN MFTHQYLQPS R

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 687-757 of mouse Mitofusin 2 (NP_573464.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MFN2

Target: MFN2 (Mitofusin 2 (MFN2))

Andere Bezeichnung: MFN2 (MFN2 Produkte)

Hintergrund: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.,MFN2,CMT2A,CMT2A2,CMT2A2A,CMT2A2B,CPRP1,HMSN6A,HSG,MARF,mitofusin-2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitophagy fission and fusion,Neuroscience,Neurodegenerative Diseases,Mitochondrial Control of Autophagy,MFN2

Molekulargewicht: 68 kDa/86 kDa

Gen-ID: 170731

Pathways: Skeletal Muscle Fiber Development