PERB11.2 antikoerper, MHC class I polypeptide-related sequence B antikoerper, MHC class I-related protein-like antikoerper, MICB antikoerper, LOC512825 antikoerper
Hintergrund
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.,MICB,PERB11.2,Immunology & Inflammation,MICB