MLH3 Antikörper (AA 1180-1429)

Produktnummer ABIN6143878

Produktdetails anti-MLH3 Antikörper

Target: MLH3 (MutL Homolog 3 (MLH3))

Bindungsspezifität: AA 1180-1429

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLH3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RFTKGMIHSM QVLQQVDNKF IACLMSTKTE ENGEADSYEK QQAQGSGRKK LLSSTLIPPL EITVTEEQRR LLWCYHKNLE DLGLEFVFPD TSDSLVLVGK VPLCFVEREA NELRRGRSTV TKSIVEEFIR EQLELLQTTG GIQGTLPLTV QKVLASQACH GAIKFNDGLS LQESCRLIEA LSSCQLPFQC AHGRPSMLPL ADIDHLEQEK QIKPNLTKLR KMAQAWRLFG KAECDTRQSL QQSMPPCEPP

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1180-1429 of human MLH3 (NP_055196.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MLH3

Target: MLH3 (MutL Homolog 3 (MLH3))

Andere Bezeichnung: MLH3 (MLH3 Produkte)

Synonyme: AV125803 antikoerper, BB126472 antikoerper, MGC80774 antikoerper, MLH3 antikoerper, HNPCC7 antikoerper, mutL homolog 3 antikoerper, mutL homolog 3 L homeolog antikoerper, Mlh3 antikoerper, mlh3.L antikoerper, MLH3 antikoerper, mlh3 antikoerper

Hintergrund: This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.,MLH3,HNPCC7,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MLH3

Molekulargewicht: 161 kDa/163 kDa

Gen-ID: 27030

UniProt: Q9UHC1

Pathways: Chromatin Binding