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MR1 Antikörper (AA 20-260)

MR1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6143983
  • Target Alle MR1 Antikörper anzeigen
    MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
    Bindungsspezifität
    • 11
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 20-260
    Reaktivität
    • 37
    • 5
    • 4
    Human
    Wirt
    • 30
    • 7
    Kaninchen
    Klonalität
    • 31
    • 6
    Polyklonal
    Konjugat
    • 15
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MR1 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 23
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    SDSRTHSLRY FRLGVSDPIH GVPEFISVGY VDSHPITTYD SVTRQKEPRA PWMAENLAPD HWERYTQLLR GWQQMFKVEL KRLQRHYNHS DNVAHTIKQA WEANQHELLY QKNWLEEECI AWLKRFLEYG KDTLQRTEPP LVRVNRKETF PGVTALFCKA HGFYPPEIYM TWMKNGEEIV QEIDYGDILP SGDGTYQAWA SIELDPQSSN LYSCHVEHCG VHMVLQVPQE SETIPLVMKA V
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 20-260 of human MR1 (NP_001181928.1).
    Isotyp
    IgG
    Top Product
    Discover our top product MR1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
    Andere Bezeichnung
    MR1 (MR1 Produkte)
    Synonyme
    YFV antikoerper, hlals antikoerper, MGC154362 antikoerper, MR1 antikoerper, DKFZp468C1823 antikoerper, HLALS antikoerper, H2ls antikoerper, Hlals antikoerper, MHC class I antigen YF5 antikoerper, major histocompatibility complex, class I-related antikoerper, major histocompatibility complex, class I-related L homeolog antikoerper, YF5 antikoerper, MR1 antikoerper, mr1.L antikoerper, mr1 antikoerper, Mr1 antikoerper
    Hintergrund
    MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.,MR1,HLALS,Immunology & Inflammation,MR1
    Molekulargewicht
    25 kDa/28 kDa/34 kDa/39 kDa
    Gen-ID
    3140
    UniProt
    Q95460
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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