MUS81 Antikörper (AA 1-350)

Produktnummer ABIN6144202

Produktdetails anti-MUS81 Antikörper

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Bindungsspezifität: AA 1-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUS81 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MAAPVRLGRK RPLPACPNPL FVRWLTEWRD EATRSRRRTR FVFQKALRSL RRYPLPLRSG KEAKILQHFG DGLCRMLDER LQRHRTSGGD HAPDSPSGEN SPAPQGRLAE VQDSSMPVPA QPKAGGSGSY WPARHSGARV ILLVLYREHL NPNGHHFLTK EELLQRCAQK SPRVAPGSAR PWPALRSLLH RNLVLRTHQP ARYSLTPEGL ELAQKLAESE GLSLLNVGIG PKEPPGEETA VPGAASAELA SEAGVQQQPL ELRPGEYRVL LCVDIGETRG GGHRPELLRE LQRLHVTHTV RKLHVGDFVW VAQETNPRDP ANPGELVLDH IVERKRLDDL CSSIIDGRFR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human MUS81 (NP_079404.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MUS81

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Andere Bezeichnung: MUS81 (MUS81 Produkte)

Synonyme: CG3026 antikoerper, Dmel\\CG3026 antikoerper, EG:BACR7A4.16 antikoerper, MUS81 antikoerper, GB15332 antikoerper, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 antikoerper, ATMUS81 antikoerper, F6I18.220 antikoerper, F6I18_220 antikoerper, MMS AND UV SENSITIVE 81 antikoerper, SLX3 antikoerper, slx3 antikoerper, 1200008A18Rik antikoerper, AI182501 antikoerper, AW045863 antikoerper, wu:fc26g01 antikoerper, zgc:66489 antikoerper, zgc:91801 antikoerper, CG3026 gene product from transcript CG3026-RA antikoerper, MUS81 structure-specific endonuclease subunit antikoerper, crossover junction endonuclease MUS81 antikoerper, Restriction endonuclease, type II-like superfamily protein antikoerper, Mus81p antikoerper, Holliday junction resolvase subunit Mus81 antikoerper, MUS81 protein antikoerper, hypothetical protein antikoerper, mus81 antikoerper, MUS81 antikoerper, LOC725951 antikoerper, Mus81 antikoerper, CAALFM_C600540WA antikoerper

Hintergrund: This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.,MUS81,SLX3,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,MUS81

Molekulargewicht: 61 kDa

Gen-ID: 80198

UniProt: Q96NY9

Pathways: DNA Reparatur