MYD88 Antikörper (AA 60-309)

Produktnummer ABIN6144228

Produktdetails anti-MYD88 Antikörper

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Bindungsspezifität: AA 60-309

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYD88 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: WTALAEEMDF EYLEIRQLET QADPTGRLLD AWQGRPGASV GRLLELLTKL GRDDVLLELG PSIEEDCQKY ILKQQQEEAE KPLQVAAVDS SVPRTAELAG ITTLDDPLGH MPERFDAFIC YCPSDIQFVQ EMIRQLEQTN YRLKLCVSDR DVLPGTCVWS IASELIEKRC RRMVVVVSDD YLQSKECDFQ TKFALSLSPG AHQKRLIPIK YKAMKKEFPS ILRFITVCDY TNPCTKSWFW TRLAKALSLP

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-309 of human MyD88 (NP_002459.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MYD88

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Andere Bezeichnung: MYD88 (MYD88 Produkte)

Hintergrund: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.,MYD88,MYD88D,myeloid differentiation primary response 88,MyD88,Signal Transduction,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,MYD88

Molekulargewicht: 15 kDa/20 kDa/28 kDa/31 kDa/33 kDa/34 kDa

Gen-ID: 4615

UniProt: Q99836

Pathways: NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades