MYH11 Antikörper (AA 1680-1979)

Produktnummer ABIN6144234

Produktdetails anti-MYH11 Antikörper

Target: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Bindungsspezifität: AA 1680-1979

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYH11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: ATAKENEKKA KSLEADLMQL QEDLAAAERA RKQADLEKEE LAEELASSLS GRNALQDEKR RLEARIAQLE EELEEEQGNM EAMSDRVRKA TQQAEQLSNE LATERSTAQK NESARQQLER QNKELRSKLH EMEGAVKSKF KSTIAALEAK IAQLEEQVEQ EAREKQAATK SLKQKDKKLK EILLQVEDER KMAEQYKEQA EKGNARVKQL KRQLEEAEEE SQRINANRRK LQRELDEATE SNEAMGREVN ALKSKLRRGN ETSFVPSRRS GGRRVIENAD GSEEETDTRD ADFNGTKASE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1680-1979 of human SMMHC/SMMHC/MYH11 (NP_001035203.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MYH11

Target: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Andere Bezeichnung: MYH11 (MYH11 Produkte)

Synonyme: AV071570 antikoerper, SM1 antikoerper, SM2 antikoerper, smMHC antikoerper, AAT4 antikoerper, FAA4 antikoerper, SMHC antikoerper, SMMHC antikoerper, myosin antikoerper, myh11 antikoerper, myosin, heavy polypeptide 11, smooth muscle antikoerper, myosin heavy chain 11 antikoerper, myosin, heavy chain 11, smooth muscle antikoerper, myosin, heavy chain 11a, smooth muscle antikoerper, Myh11 antikoerper, MYH11 antikoerper, myh11a antikoerper

Hintergrund: The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.,MYH11,AAT4,FAA4,SMHC,SMMHC,myosin-11,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Stem Cells,Cardiovascular,Cardiovascular Markers,Smooth Muscle Cells,Heart,Contractility,MYH11

Molekulargewicht: 223 kDa/224 kDa/227 kDa/228 kDa

Gen-ID: 4629

UniProt: P35749