MYLK Antikörper (AA 1765-1914)

Produktnummer ABIN6144264

Produktdetails anti-MYLK Antikörper

Target: MYLK (Myosin Light Chain Kinase (MYLK))

Bindungsspezifität: AA 1765-1914

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYLK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SGLSGRKSST GSPTSPLNAE KLESEEDVSQ AFLEAVAEEK PHVKPYFSKT IRDLEVVEGS AARFDCKIEG YPDPEVVWFK DDQSIRESRH FQIDYDEDGN CSLIISDVCG DDDAKYTCKA VNSLGEATCT AELIVETMEE GEGEGEEEEE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1765-1914 of human MYLK (NP_444253.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MYLK

Target: MYLK (Myosin Light Chain Kinase (MYLK))

Andere Bezeichnung: MYLK (MYLK Produkte)

Hintergrund: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.,MYLK,AAT7,KRP,MLCK,MLCK1,MLCK108,MLCK210,MSTP083,MYLK1,s mMLCK,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Actins,MYLK

Molekulargewicht: 16 kDa/80 kDa/110 kDa/197-210 kDa

Gen-ID: 4638

UniProt: Q15746