Myosin VI Antikörper (AA 1016-1285)

Produktnummer ABIN6144291

Produktdetails anti-Myosin VI Antikörper

Target: Myosin VI (MYO6)

Bindungsspezifität: AA 1016-1285

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myosin VI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IAQSEAELIS DEAQADLALR RNDGTRPKMT PEQMAKEMSE FLSRGPAVLA TKAAAGTKKY DLSKWKYAEL RDTINTSCDI ELLAACREEF HRRLKVYHAW KSKNKKRNTE TEQRAPKSVT DYDFAPFLNN SPQQNPAAQI PARQREIEMN RQQRFFRIPF IRPADQYKDP QSKKKGWWYA HFDGPWIARQ MELHPDKPPI LLVAGKDDME MCELNLEETG LTRKRGAEIL PRQFEEIWER CGGIQYLQNA IESRQARPTY ATAMLQSLLK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1285 of human MYO6 (NP_004990.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Myosin VI

Target: Myosin VI (MYO6)

Andere Bezeichnung: MYO6 (MYO6 Produkte)

Hintergrund: This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,MYO6,DFNA22,DFNB37,Myo6-007,Myo6-008,myosin VI,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYO6

Molekulargewicht: 145 kDa/146 kDa/148 kDa/149 kDa

Gen-ID: 4646

UniProt: Q9UM54

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization