Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

N4BP1 Antikörper (AA 190-590)

N4BP1 Reaktivität: Maus WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6144311
  • Target Alle N4BP1 Antikörper anzeigen
    N4BP1 (NEDD4 Binding Protein 1 (N4BP1))
    Bindungsspezifität
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 190-590
    Reaktivität
    • 15
    • 1
    • 1
    Maus
    Wirt
    • 14
    • 1
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser N4BP1 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    TQGEESLFET DDDVITVGDV RPPEYTQSAA TGPSSARDEV VVQEDSRNKA RTPVSELTKH MDTVFSSSPD VLFVPVNGLS PDEDALSKDR VCHKRRSSDT EERHTKKQFS LENVPEGELL PDGKGSAGNE VIDLSDPASN STNLSPDGKD TTEEMEYNIL VNFFKTMGYS QEIVEKVIRE YGPSTEPLLL LEEIEKENKR LQEDRDFPPC TVYPDASQSR NAGVGSTTNE LTADSTPKKA QSHTEQSMVE RFSQLPFKDS KHCTSNCKVN SFRTVPVGQK QEIWGSKQNS SCTVDLETDG HSASAASASP KDISFVSRGA SGHQQRNPAF PENGFQQQTE PLLPNNTKPA CEKRSGSCSS PQPKPNYPPL SPPLPLPQLL PSVTEARLGG SSDHIDSSVT G
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 190-590 of mouse N4BP1 (NP_085040.2).
    Isotyp
    IgG
    Top Product
    Discover our top product N4BP1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    N4BP1 (NEDD4 Binding Protein 1 (N4BP1))
    Andere Bezeichnung
    N4BP1 (N4BP1 Produkte)
    Synonyme
    AI481586 antikoerper, C81621 antikoerper, RGD1305179 antikoerper, wu:fi03b05 antikoerper, zgc:66437 antikoerper, NEDD4 binding protein 1 antikoerper, Nedd4 binding protein 1 antikoerper, nedd4 binding protein 1 antikoerper, nedd4 binding protein 1 L homeolog antikoerper, N4BP1 antikoerper, N4bp1 antikoerper, n4bp1 antikoerper, n4bp1.L antikoerper
    Hintergrund
    Potent suppressor of cytokine production that acts as a regulator of innate immune signaling and inflammation. Acts as a key negative regulator of select cytokine and chemokine responses elicited by TRIF-independent Toll-like receptors (TLRs, thereby limiting inflammatory cytokine responses to minor insults. In response to more threatening pathogens, cleaved by CASP8 downstream of TLR3 or TLR4, leading to its inactivation, thereby allowing production of inflammatory cytokines (By similarity. Acts as a restriction factor against some viruses, such as HIV-1: restricts HIV-1 replication by binding to HIV-1 mRNAs and mediating their degradation via its ribonuclease activity. Also acts as an inhibitor of the E3 ubiquitin-protein ligase ITCH: acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity.,N4BP1,Epigenetics & Nuclear Signaling,N4BP1
    Molekulargewicht
    99 kDa
    Gen-ID
    80750
    UniProt
    O75113
Sie sind hier:
Kundenservice