NCOR2 Antikörper (AA 670-900)

Produktnummer ABIN6144422

Produktdetails anti-NCOR2 Antikörper

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Bindungsspezifität: AA 670-900

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: KLKMEKERNA RRKKKKAPAA ASEEAAFPPV VEDEEMEASG VSGNEEEMVE EAEALHASGN EVPRGECSGP ATVNNSSDTE SIPSPHTEAA KDTGQNGPKP PATLGADGPP PGPPTPPPED IPAPTEPTPA SEATGAPTPP PAPPSPSAPP PVVPKEEKEE ETAAAPPVEE GEEQKPPAAE ELAVDTGKAE EPVKSECTEE AEEGPAKGKD AEAAEATAEG ALKAEKKEGG S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 670-900 of human NCOR2 (NP_006303.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NCOR2

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Andere Bezeichnung: NCOR2 (NCOR2 Produkte)

Synonyme: CTG26 antikoerper, N-CoR2 antikoerper, SMAP270 antikoerper, SMRT antikoerper, SMRTE antikoerper, SMRTE-tau antikoerper, TNRC14 antikoerper, TRAC antikoerper, TRAC-1 antikoerper, TRAC1 antikoerper, N-CoR antikoerper, SMRTe antikoerper, NCOR2 antikoerper, gb:be017685 antikoerper, si:bz71m17.2 antikoerper, smrt antikoerper, ctg26 antikoerper, smrte antikoerper, trac1 antikoerper, tnrc14 antikoerper, trac-1 antikoerper, smrte-tau antikoerper, nuclear receptor corepressor 2 antikoerper, nuclear receptor co-repressor 2 antikoerper, NCOR2 antikoerper, Ncor2 antikoerper, ncor2 antikoerper

Hintergrund: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.,NCOR2,CTG26,N-CoR2,SMAP270,SMRT,SMRTE,SMRTE-tau,TNRC14,TRAC,TRAC-1,TRAC1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Notch Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,NCOR2

Molekulargewicht: 81 kDa/268 kDa/273 kDa/274 kDa

Gen-ID: 9612

UniProt: Q9Y618

Pathways: Notch Signalweg, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha