NLRP11 Antikörper (AA 420-600)

Produktnummer ABIN6144660

Produktdetails anti-NLRP11 Antikörper

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Bindungsspezifität: AA 420-600

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: VGFTEADVSV LQAANILLPS NTHKDRYKFI HLNVQEFCTA IAFLMAVPNY LIPSGSREYK EKREQYSDFN QVFTFIFGLL NANRRKILET SFGYQLPMVD SFKWYSVGYM KHLDRDPEKL THHMPLFYCL YENREEEFVK TIVDALMEVT VYLQSDKDMM VSLYCLDYCC HLRTLKLSVQ R

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 420-600 of human NLRP11 (NP_659444.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NLRP11

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Andere Bezeichnung: NLRP11 (NLRP11 Produkte)

Synonyme: CLR19.6 antikoerper, NALP11 antikoerper, NOD17 antikoerper, PAN10 antikoerper, PYPAF6 antikoerper, PYPAF7 antikoerper, NLR family pyrin domain containing 11 antikoerper, NLRP11 antikoerper

Hintergrund: This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms.,NLRP11,CLR19.6,NALP11,NOD17,PAN10,PYPAF6,PYPAF7,Epigenetics & Nuclear Signaling,RNA Binding,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,NLRP11

Molekulargewicht: 105 kDa/111 kDa/117 kDa

Gen-ID: 204801

UniProt: P59045

Pathways: Inflammasome