NR1I3 Antikörper (AA 103-352)
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- Target Alle NR1I3 Antikörper anzeigen
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
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Bindungsspezifität
- AA 103-352
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NR1I3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- PVQLSKEQEE LIRTLLGAHT RHMGTMFEQF VQFRPPAHLF IHHQPLPTLA PVLPLVTHFA DINTFMVLQV IKFTKDLPVF RSLPIEDQIS LLKGAAVEIC HIVLNTTFCL QTQNFLCGPL RYTIEDGARV SPTVGFQVEF LELLFHFHGT LRKLQLQEPE YVLLAAMALF SPDRPGVTQR DEIDQLQEEM ALTLQSYIKG QQRRPRDRFL YAKLLGLLAE LRSINEAYGY QIQHIQGLSA MMPLLQEICS
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 103-352 of human NR1I3 (NP_001070948.1).
- Isotyp
- IgG
- Top Product
- Discover our top product NR1I3 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
- Andere Bezeichnung
- NR1I3 (NR1I3 Produkte)
- Synonyme
- AA209988 antikoerper, AI551208 antikoerper, CAR antikoerper, CAR-beta antikoerper, Care2 antikoerper, ESTM32 antikoerper, MB67 antikoerper, CAR1 antikoerper, CXR antikoerper, nuclear receptor subfamily 1 group I member 3 antikoerper, nuclear receptor subfamily 1, group I, member 3 antikoerper, NR1I3 antikoerper, Nr1i3 antikoerper
- Hintergrund
- This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.,NR1I3,CAR,CAR1,NR1I3,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,NR1I3
- Molekulargewicht
- 30-40 kDa
- Gen-ID
- 9970
- UniProt
- Q14994
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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