ORAI1 Antikörper (AA 202-301)

Produktnummer ABIN6145053

Produktdetails anti-ORAI1 Antikörper

Target: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Bindungsspezifität: AA 202-301

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORAI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LKKQPGQPRP TSKPPASGAA ANVSTSGITP GQAAAIASTT IMVPFGLIFI VFAVHFYRSL VSHKTDRQFQ ELNELAEFAR LQDQLDHRGD HPLTPGSHYA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 202-301 of human ORAI1 (NP_116179.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ORAI1

Target: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Andere Bezeichnung: ORAI1 (ORAI1 Produkte)

Synonyme: CRACM1 antikoerper, ORAT1 antikoerper, TMEM142A antikoerper, RGD1311873 antikoerper, D730049H07Rik antikoerper, Tmem142a antikoerper, orai-1 antikoerper, im:7146264 antikoerper, orai1 antikoerper, tmem142a antikoerper, zgc:109721 antikoerper, orai2 antikoerper, ORAI1 antikoerper, LOC100218031 antikoerper, ORAI calcium release-activated calcium modulator 1 antikoerper, ORAI calcium release-activated calcium modulator 1b antikoerper, ORAI calcium release-activated calcium modulator 1 S homeolog antikoerper, ORAI1 antikoerper, Orai1 antikoerper, orai1b antikoerper, orai1.S antikoerper, orai1 antikoerper

Hintergrund: The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).,CRACM1,IMD9,ORAT1,TAM2,TMEM142A,ORAI1,Signal Transduction,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,ORAI1

Molekulargewicht: 25 kDa/32 kDa

Gen-ID: 84876

UniProt: Q96D31

Pathways: T-Zell Rezeptor Signalweg, BCR Signaling