PABPN1 Antikörper (AA 1-100)
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- Target Alle PABPN1 Antikörper anzeigen
- PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
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Bindungsspezifität
- AA 1-100
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PABPN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MAAAAAAAAA AGAAGGRGSG PGRRRHLVPG AGGEAGEGAP GGAGDYGNGL ESEELEPEEL LLEPEPEPEP EEEPPRPRAP PGAPGPGPGS GAPGSQEEEE
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PABPN1 (NP_004634.1).
- Isotyp
- IgG
- Top Product
- Discover our top product PABPN1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:1000
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." in: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).
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ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." in: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).
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- Target
- PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
- Andere Bezeichnung
- PABPN1 (PABPN1 Produkte)
- Hintergrund
- This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.,PABPN1,OPMD,PAB2,PABII,PABP-2,PABP2,Epigenetics & Nuclear Signaling,RNA Binding,PABPN1
- Molekulargewicht
- 31 kDa/32 kDa/37 kDa
- Gen-ID
- 8106
- UniProt
- Q86U42
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