PBX1 Antikörper (AA 311-430)

Produktnummer ABIN6145269

Produktdetails anti-PBX1 Antikörper

Target: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Bindungsspezifität: AA 311-430

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PBX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VTATNVSAHG SQANSPSTPN SAGSSSSFNM SNSGDLFMSV QSLNGDSYQG AQVGANVQSQ VDTLRHVISQ TGGYSDGLAA SQMYSPQGIS ANGGWQDATT PSSVTSPTEG PGSVHSDTSN

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 311-430 of human PBX1 (NP_002576.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PBX1

Target: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Andere Bezeichnung: PBX1 (PBX1 Produkte)

Synonyme: fi29e01 antikoerper, pbx1b antikoerper, wu:fi29e01 antikoerper, zgc:55265 antikoerper, 2310056B04Rik antikoerper, AI848790 antikoerper, AU015730 antikoerper, D230003C07Rik antikoerper, Pbx-1 antikoerper, Pbx1a antikoerper, Pbx1b antikoerper, PBX1A antikoerper, Xpbx1 antikoerper, Xpbx1b antikoerper, PBX homeobox 1 antikoerper, pre-B-cell leukemia homeobox 1a antikoerper, pre B cell leukemia homeobox 1 antikoerper, pre-B-cell leukemia homeobox 1 S homeolog antikoerper, PBX1 antikoerper, pbx1a antikoerper, Pbx1 antikoerper, pbx1.S antikoerper

Hintergrund: This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t(1,19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PBX1,Epigenetics & Nuclear Signaling,Transcription Factors,Stem Cells,Hematopoietic Progenitors,PBX1

Molekulargewicht: 38 kDa/46 kDa

Gen-ID: 5087

UniProt: P40424