PCDHA12 Antikörper (AA 713-792)

Produktnummer ABIN6145297

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PCDHA12 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PCDHA12 Antikörper (AA 713-792) (ABIN6145297)

Target: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHA12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PCDHA12 Antikörper

Bindungsspezifität: AA 713-792

Sequenz: LTLLLYTALR CSAPPTVSRC APGKPTLVCS SAVGSWSYSQ QRRQRVCSAE SPPKTDLMAF SPSLQLSRED CLNPPSEVSY

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 713-792 of human PCDHA12 (NP_114070.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PCDHA12

Target: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Andere Bezeichnung: PCDHA12

Hintergrund: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.,PCDHA12,PCDH-ALPHA12,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell Adhesion,Cadherins,Cytoskeleton,Neuroscience,Calcium Signaling,PCDHA12

Molekulargewicht: 85 kDa/101 kDa

Gen-ID: 56137

UniProt: Q9UN75