PCM1 Antikörper (AA 1-260)

Produktnummer ABIN6145315

Produktdetails anti-PCM1 Antikörper

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Bindungsspezifität: AA 1-260

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MATGGGPFED GMNDQDLPNW SNENVDDRLN NMDWGAQQKK ANRSSEKNKK KFGVESDKRV TNDISPESSP GVGRRRTKTP HTFPHSRYMS QMSVPEQAEL EKLKQRINFS DLDQRSIGSD SQGRATAANN KRQLSENRKP FNFLPMQINT NKSKDASTSP PNRETIGSAQ CKELFASALS NDLLQNCQVS EEDGRGEPAM ESSQIVSRLV QIRDYITKAS SMREDLVEKN ERSANVERLT HLIDHLKEQE KSYMKFLKKI

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PCM1 (NP_006188.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PCM1

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Andere Bezeichnung: PCM1 (PCM1 Produkte)

Synonyme: wu:fb30g01 antikoerper, wu:fb94e03 antikoerper, wu:fe14f07 antikoerper, PCM1 antikoerper, ptc4 antikoerper, pcm-1 antikoerper, PTC4 antikoerper, 2600002H09Rik antikoerper, 9430077F19Rik antikoerper, C030044G17Rik antikoerper, PCM-1 antikoerper, pericentriolar material 1 antikoerper, pericentriolar material 1 L homeolog antikoerper, pcm1 antikoerper, PCM1 antikoerper, Pcm1 antikoerper, pcm1.L antikoerper

Hintergrund: The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.,PCM1,PTC4,RET/PCM-1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,PCM1

Molekulargewicht: 59 kDa/222 kDa/228 kDa

Gen-ID: 5108

UniProt: Q15154

Pathways: Stem Cell Maintenance, M Phase, Maintenance of Protein Location