PEG3 Antikörper (AA 1-300)

Produktnummer ABIN6145434

Produktdetails anti-PEG3 Antikörper

Target: PEG3 (Paternally Expressed 3 (PEG3))

Bindungsspezifität: AA 1-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MLPPKHLSAT KPKKSWAPNL YELDSDLTKE PDVIIGEGPT DSEFFHQRFR NLIYVEFVGP RKTLIKLRNL CLDWLQPETR TKEEIIELLV LEQYLTIIPE KLKPWVRAKK PENCEKLVTL LENYKEMYQP EDDNNSDVTS DDDMTRNRRE SSPPHSVHSF SDRDWDRRGR SRDMEPRDRW SHTRNPRSRM PPRDLSLPVV AKTSFEMDRE DDRDSRAYES RSQDAESYQN VVDLAEDRKP HNTIQDNMEN YRKLLSLVQL AEDDGHSHMT QGHSSRSKRS AYPSTSRGLK TMPEAKKSTH

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PEG3 (NP_006201.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Andere Bezeichnung: PEG3 (PEG3 Produkte)

Synonyme: PW1 antikoerper, ZKSCAN22 antikoerper, ZNF904 antikoerper, ZSCAN24 antikoerper, AL022617 antikoerper, ASF-1 antikoerper, End4 antikoerper, Gcap4 antikoerper, Pw1 antikoerper, Zfp102 antikoerper, mKIAA0287 antikoerper, PEG3 antikoerper, paternally expressed 3 antikoerper, paternally-expressed gene 3 protein antikoerper, PEG3 antikoerper, Peg3 antikoerper, LOC100448879 antikoerper

Hintergrund: In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.,PEG3,PW1,ZKSCAN22,ZNF904,ZSCAN24,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,PEG3

Molekulargewicht: 60 kDa/165 kDa/166 kDa/180 kDa

Gen-ID: 5178

UniProt: Q9GZU2