PFKM Antikörper (AA 501-780)

Produktnummer ABIN6145488

Produktdetails anti-PFKM Antikörper

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Bindungsspezifität: AA 501-780

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: AYTGGLELME GRKQFDELCI PFVVIPATVS NNVPGSDFSV GADTALNTIC TTCDRIKQSA AGTKRRVFII ETMGGYCGYL ATMAGLAAGA DAAYIFEEPF TIRDLQANVE HLVQKMKTTV KRGLVLRNEK CNENYTTDFI FNLYSEEGKG IFDSRKNVLG HMQQGGSPTP FDRNFATKMG AKAMNWMSGK IKESYRNGRI FANTPDSGCV LGMRKRALVF QPVAELKDQT DFEHRIPKEQ WWLKLRPILK ILAKYEIDLD TSDHAHLEHI TRKRSGEAAV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 501-780 of human PFKM (NP_001160160.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PFKM

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Andere Bezeichnung: PFKM (PFKM Produkte)

Synonyme: GSD7 antikoerper, PFK-1 antikoerper, PFK1 antikoerper, PFKA antikoerper, PFKX antikoerper, AI131669 antikoerper, PFK-A antikoerper, PFK-M antikoerper, Pfk-4 antikoerper, Pfk4 antikoerper, Pfka antikoerper, Pfkx antikoerper, Pfk-M antikoerper, M-PFK antikoerper, PFKM antikoerper, pfkm antikoerper, zgc:92344 antikoerper, pfk antikoerper, im:7137110 antikoerper, wu:fc58g11 antikoerper, phosphofructokinase, muscle antikoerper, phosphofructokinase, platelet antikoerper, phosphofructokinase, muscle a antikoerper, phosphofructokinase, muscle S homeolog antikoerper, phosphofructokinase, muscle b antikoerper, PFKM antikoerper, Pfkm antikoerper, PFKP antikoerper, pfkma antikoerper, pfkm.S antikoerper, pfkmb antikoerper

Hintergrund: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.,PFKM,ATP-PFK,GSD7,PFK-1,PFK1,PFKA,PFKX,PPP1R122,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,PFKM

Molekulargewicht: 81 kDa/85 kDa/93 kDa

Gen-ID: 5213

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effekt