PHOX2B Antikörper (AA 1-90)

Produktnummer ABIN6145577

Produktdetails anti-PHOX2B Antikörper

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Bindungsspezifität: AA 1-90

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHOX2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MYKMEYSYLN SSAYESCMAG MDTSSLASAY ADFSSCSQAS GFQYNPIRTT FGATSGCPSL TPGSCSLGTL RDHQSSPYAA VPYKLFTDHG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PHOX2B (NP_003915.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Andere Bezeichnung: PHOX2B (PHOX2B Produkte)

Hintergrund: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.,PHOX2B,NBLST2,NBPhox,PMX2B,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Neuroscience,PHOX2B

Molekulargewicht: 31 kDa

Gen-ID: 8929

UniProt: Q99453