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RUNX2 Antikörper (AA 251-351)

RUNX2 Reaktivität: Human WB, IF, IHC (p), EIA Wirt: Maus Monoclonal 1D2 unconjugated
Produktnummer ABIN614560
  • Target Alle RUNX2 Antikörper anzeigen
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    Bindungsspezifität
    • 16
    • 16
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-351
    Reaktivität
    • 115
    • 46
    • 30
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 106
    • 11
    Maus
    Klonalität
    • 99
    • 18
    Monoklonal
    Konjugat
    • 59
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RUNX2 Antikörper ist unkonjugiert
    Applikation
    • 91
    • 46
    • 31
    • 25
    • 10
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    Recognizes Runt-related Transcription Factor 2 (RUNX2).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Protein A Chromatography
    Immunogen
    Partial Recombinant RUNX2 (NP_004339, 251 a.a. ~ 351 a.a) protein with GST tag.
    Klon
    1D2
    Isotyp
    IgG2a
    Top Product
    Discover our top product RUNX2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, pH 7.2
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    Andere Bezeichnung
    RUNX2 (RUNX2 Produkte)
    Hintergrund
    RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX2 is essential for skeletal mineralization in that it stimulates osteoblast differentiation of mesenchymal stem cells, promotes chondrocyte hypertrophy and contributes to endothelial cell migration and vascular invasion of developing bones. Regulating RUNX2 expression may be a useful therapeutic tool for promoting bone formation. Mutations in the C-terminus of RUNX2 are associated with cleidocranial dysplasia syndrome, an autosomal-dominant skeletal dysplasia syndrome that is characterized by widely patent calvarial sutures, clavicular hypoplasia, supernumerary teeth, and short stature.Synonyms: AML-3, AML3, Acute myeloid leukemia 3 protein, CBFA1, Core-binding factor subunit alpha-1, OSF-2, OSF2, Osteoblast-specific transcription factor 2, PEA2-alpha A, PEBP2-alpha A, PEBP2A, Polyomavirus enhancer-binding protein 2 alpha A subunit, Runt-related transcription factor 2, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit
    Gen-ID
    860
    NCBI Accession
    NP_001015051
    UniProt
    Q13950
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