PIAS4 Antikörper (AA 60-260)

Produktnummer ABIN6145602

Produktdetails anti-PIAS4 Antikörper

Target: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Bindungsspezifität: AA 60-260

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIAS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ELYETRYAKK NSEPAPQPHR PLDPLTMHST YDRAGAVPRT PLAGPNIDYP VLYGKYLNGL GRLPAKTLKP EVRLVKLPFF NMLDELLKPT ELVPQNNEKL QESPCIFALT PRQVELIRNS RELQPGVKAV QVVLRICYSD TSCPQEDQYP PNIAVKVNHS YCSVPGYYPS NKPGVEPKRP CRPINLTHLM YLSSATNRIT V

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-260 of human PIAS4 (NP_056981.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PIAS4

Target: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Andere Bezeichnung: PIAS4 (PIAS4 Produkte)

Synonyme: PIASY antikoerper, Piasg antikoerper, ZMIZ6 antikoerper, pias4 antikoerper, piasy antikoerper, wu:fc54c11 antikoerper, wu:fi18c10 antikoerper, wu:fi20e09 antikoerper, wu:fk93f11 antikoerper, zgc:66410 antikoerper, piasg antikoerper, zmiz6 antikoerper, LOC100219439 antikoerper, Pias-gamma antikoerper, pias4l antikoerper, wu:fi26h11 antikoerper, zgc:63923 antikoerper, protein inhibitor of activated STAT 4 antikoerper, protein inhibitor of activated STAT, 4 antikoerper, protein inhibitor of activated STAT, 4a antikoerper, protein inhibitor of activated STAT 4 L homeolog antikoerper, protein inhibitor of activated STAT, 4b antikoerper, PIAS4 antikoerper, Pias4 antikoerper, pias4a antikoerper, pias4.L antikoerper, pias4 antikoerper, pias4b antikoerper

Hintergrund: Functions as an E3-type small ubiquitin-like modifier (SUMO ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.,PIAS4,PIAS-gamma,PIASY,Piasg,ZMIZ6,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,NF-kB Signaling Pathway,PIAS4

Molekulargewicht: 56 kDa

Gen-ID: 51588

UniProt: Q8N2W9

Pathways: JAK-STAT Signalweg, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus