PKM Antikörper (AA 11-221)

Produktnummer ABIN6145714

Produktdetails anti-PKM Antikörper

Target: PKM (Pyruvate Kinase M1/2 (PKM))

Bindungsspezifität: AA 11-221

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: AFIQTQQLHA AMADTFLEHM CRLDIDSPPI TARNTGIICT IGPASRSVET LKEMIKSGMN VARLNFSHGT HEYHAETIKN VRTATESFAS DPILYRPVAV ALDTKGPEIR TGLIKGSGTA EVELKKGATL KITLDNAYME KCDENILWLD YKNICKVVEV GSKIYVDDGL ISLQVKQKGA DFLVTEVENG GSLGSKKGVN LPGAAVDLPA V

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 11-221 of human PKM2 (NP_002645.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PKM

Target: PKM (Pyruvate Kinase M1/2 (PKM))

Andere Bezeichnung: PKM (PKM Produkte)

Synonyme: CTHBP antikoerper, OIP3 antikoerper, PK3 antikoerper, PKM2 antikoerper, TCB antikoerper, THBP1 antikoerper, AA414905 antikoerper, AL024370 antikoerper, AL024424 antikoerper, Pk-2 antikoerper, Pk-3 antikoerper, Pk3 antikoerper, Pkm2 antikoerper, PKM12 antikoerper, CG7070 antikoerper, Dmel\\CG7070 antikoerper, PYK antikoerper, Pyk antikoerper, cb1029 antikoerper, fj33f03 antikoerper, pkm2 antikoerper, pkm2a antikoerper, wu:fj33f03 antikoerper, MGC53388 antikoerper, PKM antikoerper, PK-S antikoerper, pk3 antikoerper, pkm2b antikoerper, zgc:92037 antikoerper, pyruvate kinase M1/2 antikoerper, pyruvate kinase, muscle antikoerper, Pyruvate kinase antikoerper, pyruvate kinase M1/2a antikoerper, pyruvate kinase PKM antikoerper, pyruvate kinase (PK) antikoerper, pyruvate kinase antikoerper, pyruvate kinase M1/2 S homeolog antikoerper, pyruvate kinase M1/2b antikoerper, PKM antikoerper, Pkm antikoerper, PyK antikoerper, pkma antikoerper, pkm antikoerper, LOC710798 antikoerper, pyk antikoerper, pk antikoerper, LOC100534543 antikoerper, pkm.S antikoerper, pkmb antikoerper

Hintergrund: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.,CTHBP,HEL-S-30,OIP3,PK3,PKM2,TCB,THBP1,PKM,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,PKM

Molekulargewicht: 56 kDa/57 kDa/58 kDa

Gen-ID: 5315

UniProt: P14618

Pathways: Warburg Effekt