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PKC zeta Antikörper (AA 453-592)

PRKCZ Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6146211
  • Target Alle PKC zeta (PRKCZ) Antikörper anzeigen
    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
    Bindungsspezifität
    • 35
    • 27
    • 13
    • 11
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 453-592
    Reaktivität
    • 111
    • 63
    • 41
    • 9
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 122
    • 3
    • 1
    Kaninchen
    Klonalität
    • 113
    • 13
    Polyklonal
    Konjugat
    • 57
    • 9
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PKC zeta Antikörper ist unkonjugiert
    Applikation
    • 95
    • 54
    • 33
    • 26
    • 26
    • 20
    • 19
    • 9
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    IITDNPDMNT EDYLFQVILE KPIRIPRFLS VKASHVLKGF LNKDPKERLG CRPQTGFSDI KSHAFFRSID WDLLEKKQAL PPFQPQITDD YGLDNFDTQF TSEPVQLTPD DEDAIKRIDQ SEFEGFEYIN PLLLSTEESV
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 453-592 of human PKC zeta (NP_002735.3).
    Isotyp
    IgG
    Top Product
    Discover our top product PRKCZ Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:1000,IF,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
    Andere Bezeichnung
    PRKCZ (PRKCZ Produkte)
    Synonyme
    TPKC antikoerper, PKCzeta antikoerper, prkcz-A antikoerper, pkc-zeta antikoerper, PRKCZ antikoerper, pkc2 antikoerper, PKC-ZETA antikoerper, PKC2 antikoerper, AI098070 antikoerper, C80388 antikoerper, Pkcz antikoerper, R74924 antikoerper, aPKCzeta antikoerper, zetaPKC antikoerper, 14-3-3-zetaisoform antikoerper, r14-3-3 antikoerper, pkcz antikoerper, si:ch211-150o23.4 antikoerper, protein kinase C zeta L homeolog antikoerper, protein kinase C zeta antikoerper, protein kinase C, zeta antikoerper, prkcz.L antikoerper, PRKCZ antikoerper, prkcz antikoerper, Prkcz antikoerper
    Hintergrund
    Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.,PRKCZ,PKC-ZETA,PKC2,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Phospholipase Signaling Pathway,Protein Kinase C Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,PRKCZ
    Molekulargewicht
    46 kDa/56 kDa/67 kDa
    Gen-ID
    5590
    UniProt
    Q05513
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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