FMI antikoerper, PCP-2 antikoerper, PTP antikoerper, PTP-J antikoerper, PTP-PI antikoerper, PTP-RO antikoerper, PTPPSI antikoerper, PTPRO antikoerper, PTPU2 antikoerper, R-PTP-PSI antikoerper, R-PTP-U antikoerper, hPTP-J antikoerper, Ftp-1 antikoerper, PTP-lambda antikoerper, PTPlambda antikoerper, Pcp2 antikoerper, Ptpf antikoerper, Ptprl antikoerper, R-PTP-psi antikoerper, RPTPlambda antikoerper, RPTP-psi antikoerper, fj42a04 antikoerper, fk66g06 antikoerper, ptpru antikoerper, wu:fj42a04 antikoerper, wu:fk66g06 antikoerper, protein tyrosine phosphatase, receptor type U antikoerper, protein tyrosine phosphatase, receptor type, U antikoerper, protein tyrosine phosphatase, receptor type, U, b antikoerper, PTPRU antikoerper, Ptpru antikoerper, ptprub antikoerper
Hintergrund
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.,PTPRU,FMI,PCP-2,PTP,PTP-J,PTP-PI,PTP-RO,PTPPSI,PTPRO,PTPU2,R-PTP-PSI,R-PTP-U,hPTP-J,Signal Transduction,PTPRU