RAD23B Antikörper (AA 50-150)
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- Target Alle RAD23B Antikörper anzeigen
- RAD23B (RAD23 Homolog B (RAD23B))
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Bindungsspezifität
- AA 50-150
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAD23B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequenz
- GKILNDDTAL KEYKIDEKNF VVVMVTKPKA VSTPAPATTQ QSAPASTTAV TSSTTTTVAQ APTPVPALAP TSTPASITPA SATASSEPAP ASAAKQEKPA E
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Rad23B (NP_002865.1).
- Isotyp
- IgG
- Top Product
- Discover our top product RAD23B Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- RAD23B (RAD23 Homolog B (RAD23B))
- Andere Bezeichnung
- RAD23B (RAD23B Produkte)
- Hintergrund
- The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,RAD23B,HHR23B,HR23B,P58,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RAD23B
- Molekulargewicht
- 35 kDa/43 kDa
- Gen-ID
- 5887
- UniProt
- P54727
- Pathways
- DNA Reparatur
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