RAD23B Antikörper (AA 50-150)

Produktnummer ABIN6146632

Produktdetails anti-RAD23B Antikörper

Target: RAD23B (RAD23 Homolog B (RAD23B))

Bindungsspezifität: AA 50-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD23B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: GKILNDDTAL KEYKIDEKNF VVVMVTKPKA VSTPAPATTQ QSAPASTTAV TSSTTTTVAQ APTPVPALAP TSTPASITPA SATASSEPAP ASAAKQEKPA E

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Rad23B (NP_002865.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RAD23B

Target: RAD23B (RAD23 Homolog B (RAD23B))

Andere Bezeichnung: RAD23B (RAD23B Produkte)

Synonyme: HHR23B antikoerper, HR23B antikoerper, P58 antikoerper, 0610007D13Rik antikoerper, AV001138 antikoerper, mHR23B antikoerper, p58 antikoerper, MGC107846 antikoerper, zgc:65951 antikoerper, RAD23 homolog B, nucleotide excision repair protein antikoerper, UV excision repair protein RAD23 homolog B antikoerper, RAD23 homolog B, nucleotide excision repair protein S homeolog antikoerper, RAD23B antikoerper, Rad23b antikoerper, rd23b antikoerper, rad23b antikoerper, rad23b.S antikoerper

Hintergrund: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,RAD23B,HHR23B,HR23B,P58,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RAD23B

Molekulargewicht: 35 kDa/43 kDa

Gen-ID: 5887

UniProt: P54727

Pathways: DNA Reparatur