RPSA/Laminin Receptor Antikörper (AA 1-295)

Produktnummer ABIN6147247

Produktdetails anti-RPSA/Laminin Receptor Antikörper

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Bindungsspezifität: AA 1-295

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPSA/Laminin Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MSGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL AARAIVAIEN PADVSVISSR NTGQRAVLKF AAATGATPIA GRFTPGTFTN QIQAAFREPR LLVVTDPRAD HQPLTEASYV NLPTIALCNT DSPLRYVDIA IPCNNKGAHS VGLMWWMLAR EVLRMRGTIS REHPWEVMPD LYFYRDPEEI EKEEQAAAEK AVTKEEFQGE WTAPAPEFTA TQPEVADWSE GVQVPSVPIQ QFPTEDWSAQ PATEDWSAAP TAQATEWVGA TTDWS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human 67kDa Laminin Receptor (NP_002286.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RPSA/Laminin Receptor

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Andere Bezeichnung: RPSA (RPSA Produkte)

Synonyme: 37LRP antikoerper, 67LR antikoerper, LBP/p40 antikoerper, LRP/LR antikoerper, LamR antikoerper, rpsa antikoerper, LamR1 antikoerper, RPSA antikoerper, LAMBR antikoerper, LAMR1 antikoerper, LBP antikoerper, LRP antikoerper, NEM/1CHD4 antikoerper, SA antikoerper, lamR antikoerper, p40 antikoerper, 67kDa antikoerper, 67lr antikoerper, AL022858 antikoerper, Lamr antikoerper, Lamr1 antikoerper, Lamrl1 antikoerper, MLR antikoerper, P40 antikoerper, P40-3 antikoerper, P40-8 antikoerper, lamr1 antikoerper, zgc:55831 antikoerper, zgc:77824 antikoerper, DMRT1 antikoerper, 40S ribosomal protein SA antikoerper, 67kD laminin receptor antikoerper, ribosomal protein SA antikoerper, rssa antikoerper, rpsa antikoerper, RPSA antikoerper, Rpsa antikoerper, LOC100144340 antikoerper

Hintergrund: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.,RPSA,37LRP,67LR,ICAS,LAMBR,LAMR1,LBP,LBP/p40,LRP,LRP/LR,NEM/1CHD4,SA,lamR,p40,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis,RPSA

Molekulargewicht: 32 kDa

Gen-ID: 3921

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly