Hepcidin Antikörper (AA 25-85)

Produktnummer ABIN614727

Produktdetails anti-Hepcidin Antikörper

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Bindungsspezifität: AA 25-85

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Hepcidin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to Hepcidin Antimicrobial Peptide (HAMP).

Aufreinigung: Protein A Chromatography

Immunogen: Recombinant protein, HAMP (AAH20612, 25 a.a. ~ 85 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Genename: HAMP

Klon: 1F9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu Hepcidin

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Andere Bezeichnung: Hepcidin / HAMP (HAMP Produkte)

Synonyme: HEPC antikoerper, HFE2B antikoerper, LEAP1 antikoerper, PLTR antikoerper, Hepcidin antikoerper, Hamp1 antikoerper, Hepc antikoerper, Hepc1 antikoerper, HAMP antikoerper, hepcidin antikoerper, hamp1 antikoerper, hep1 antikoerper, hepcidin antimicrobial peptide antikoerper, hepcidin-like antikoerper, hepcidin-1 antikoerper, Ham percentage antikoerper, HAMP antikoerper, Hamp antikoerper, hamp antikoerper, LOC100135935 antikoerper, LOC106584587 antikoerper

Hintergrund: Hepcidin, an human antimicrobial peptide, contains a leader sequence, a proteolysis site and a C-terminal 25 amino acid active peptide. This peptide is most active against gram-positive bacteria, but also inhibits the growth of certain yeast and gram-negative bacteria. HAMP also functions as a signaling molecule involved in the maintenance of iron homeostasis. In conjugation with HFE it seems to regulate both intestinal iron absorption and iron storage in macrophages. Mutations in HAMP are found in juvenile hemochromatosis.Synonyms: HEPC, LEAP-1, LEAP1, Liver-expressed antimicrobial peptide, PLTR, Putative liver tumor regressor

Gen-ID: 57817

NCBI Accession: NP_066998

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis