SAG Antikörper (AA 1-405)

Produktnummer ABIN6147361

Produktdetails anti-SAG Antikörper

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Bindungsspezifität: AA 1-405

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MAASGKTSKS EPNHVIFKKI SRDKSVTIYL GNRDYIDHVS QVQPVDGVVL VDPDLVKGKK VYVTLTCAFR YGQEDIDVIG LTFRRDLYFS RVQVYPPVGA ASTPTKLQES LLKKLGSNTY PFLLTFPDYL PCSVMLQPAP QDSGKSCGVD FEVKAFATDS TDAEEDKIPK KSSVRLLIRK VQHAPLEMGP QPRAEAAWQF FMSDKPLHLA VSLNKEIYFH GEPIPVTVTV TNNTEKTVKK IKAFVEQVAN VVLYSSDYYV KPVAMEEAQE KVPPNSTLTK TLTLLPLLAN NRERRGIALD GKIKHEDTNL ASSTIIKEGI DRTVLGILVS YQIKVKLTVS GFLGELTSSE VATEVPFRLM HPQPEDPAKE SYQDANLVFE EFARHNLKDA GEAEEGKRDK NDVDE

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-405 of human SAG (NP_000532.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SAG

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Andere Bezeichnung: SAG (SAG Produkte)

Synonyme: RP47 antikoerper, S-AG antikoerper, MGC75721 antikoerper, MGC84416 antikoerper, sag antikoerper, zgc:114197 antikoerper, SAGMR antikoerper, SANTI antikoerper, ARR antikoerper, sag1 antikoerper, A930001K18Rik antikoerper, Arr1 antikoerper, Irbp antikoerper, arrestin antikoerper, S-antigen visual arrestin antikoerper, S-antigen antikoerper, S-antigen; retina and pineal gland (arrestin) antikoerper, S-antigen; retina and pineal gland (arrestin) S homeolog antikoerper, S-antigen; retina and pineal gland (arrestin) b antikoerper, S-antigen, retina and pineal gland (arrestin) antikoerper, S-antigen; retina and pineal gland (arrestin) L homeolog antikoerper, SAG antikoerper, PF10_0343 antikoerper, sag antikoerper, sag.S antikoerper, sagb antikoerper, Sag antikoerper, sag.L antikoerper

Hintergrund: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.,SAG,RP47,S-AG,Signal Transduction,G protein signaling,SAG

Molekulargewicht: 45 kDa

Gen-ID: 6295

UniProt: P10523

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling