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PAI1 Antikörper (AA 24-402)

Name: PAI1 Antikörper (AA 24-402)
Brand: antibodies-online
SKU: ABIN6147601
Price: 722.37 EUR
Availability: InStock

SERPINE1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts of Rat placenta, using PAI-1/Serpin E1 antibody (ABIN6131330, ABIN6147601, ABIN6147603 and ABIN6221802) at 1:1000 dilution. (PAI1 Antikörper (AA 24-402))

Immunofluorescence analysis of L929 cells using PAI-1/Serpin E1 antibody (ABIN6131330, ABIN6147601, ABIN6147603 and ABIN6221802) at dilution of 1:100. (PAI1 Antikörper (AA 24-402))

Immunofluorescence analysis of human liver cancer using PAI-1/Serpin E1 Polyclonal Antibody (ABIN6131330, ABIN6147601, ABIN6147603 and ABIN6221802) at dilution of 1:100 (40x lens). (PAI1 Antikörper (AA 24-402))

3 Abbildungen

(1 reference)

Produktnummer ABIN6147601

Datenblatt (PDF)

Target Alle PAI1 (SERPINE1) Antikörper anzeigen

PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
Bindungsspezifität
15

15

7

7

6

5

5

5

4

4

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 24-402
Reaktivität
141

38

20

12

7

5

5

3

3

2

2

2

2

1

1
Human
Wirt
111

29

8

6

1
Kaninchen
Passende Sekundärantikörper
Klonalität
123

33
Polyklonal
Konjugat
84

16

16

6

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
Dieser PAI1 Antikörper ist unkonjugiert
Applikation
109

65

51

26

26

16

16

14

12

10

8

8

5

4

4

3

2

2

1

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF)

Sequenz

VHHPPSYVAH LASDFGVRVF QQVAQASKDR NVVFSPYGVA SVLAMLQLTT GGETQQQIQA AMGFKIDDKG MAPALRHLYK ELMGPWNKDE ISTTDAIFVQ RDLKLVQGFM PHFFRLFRST VKQVDFSEVE RARFIINDWV KTHTKGMISN LLGKGAVDQL TRLVLVNALY FNGQWKTPFP DSSTHRRLFH KSDGSTVSVP MMAQTNKFNY TEFTTPDGHY YDILELPYHG DTLSMFIAAP YEKEVPLSAL TNILSAQLIS HWKGNMTRLP RLLVLPKFSL ETEVDLRKPL ENLGMTDMFR QFQADFTSLS DQEPLHVAQA LQKVKIEVNE SGTVASSSTA VIVSARMAPE EIIMDRPFLF VVRHNPTGTV LFMGQVMEP

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Polyclonal Antibodies

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-402 of human PAI-1/Serpin E1 (NP_000593.1).

Isotyp

IgG

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SERPINE1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Yunes-Medina, Paciorkowski, Nuzbrokh, Johnson: "Depletion of transglutaminase 2 in neurons alters expression of extracellular matrix and signal transduction genes and compromises cell viability." in: Molecular and cellular neurosciences, Vol. 86, pp. 72-80, (2018) (PubMed).
Target

PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Andere Bezeichnung

SERPINE1 (SERPINE1 Produkte)

Hintergrund

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PAI,PAI-1,PAI1,PLANH1,SERPINE1,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,Endocrine and metabolic diseases,Metabolic disorders,Cardiovascular,Angiogenesis,Blood,Regulator,SERPINE1

Molekulargewicht

43 kDa/45 kDa

Gen-ID

5054

UniProt

P05121

Pathways

p53 Signalweg, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration