SET/TAF-I Antikörper (AA 146-277)
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- Target Alle SET/TAF-I (SET) Antikörper anzeigen
- SET/TAF-I (SET) (SET Nuclear Oncogene (SET))
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Bindungsspezifität
- AA 146-277
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SET/TAF-I Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequenz
- NESGDPSSKS TEIKWKSGKD LTKRSSQTQN KASRKRQHEE PESFFTWFTD HSDAGADELG EVIKDDIWPN PLQYYLVPDM DDEEGEGEED DDDDEEEEGL EDIDEEGDED EGEEDEDDDE GEEGEEDEGE DD
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 146-277 of human SET/TAF1 (NP_003002.2).
- Isotyp
- IgG
- Top Product
- Discover our top product SET Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SET/TAF-I (SET) (SET Nuclear Oncogene (SET))
- Andere Bezeichnung
- SET (SET Produkte)
- Hintergrund
- The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.,SET,2PP2A,I2PP2A,IGAAD,IPP2A2,PHAPII,TAF-I,TAF-IBETA,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,SET
- Molekulargewicht
- 30 kDa/31 kDa/32 kDa/33 kDa
- Gen-ID
- 6418
- UniProt
- Q01105
- Pathways
- Apoptose
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