SETMAR Antikörper (AA 20-300)

Produktnummer ABIN6147659

Produktdetails anti-SETMAR Antikörper

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Bindungsspezifität: AA 20-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETMAR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Sequenz: KPEAPTEQLD VACGQENLPV GAWPPGAAPA PFQYTPDHVV GPGADIDPTQ ITFPGCICVK TPCLPGTCSC LRHGENYDDN SCLRDIGSGG KYAEPVFECN VLCRCSDHCR NRVVQKGLQF HFQVFKTHKK GWGLRTLEFI PKGRFVCEYA GEVLGFSEVQ RRIHLQTKSD SNYIIAIREH VYNGQVMETF VDPTYIGNIG RFLNHSCEPN LLMIPVRIDS MVPKLALFAA KDIVPEEELS YDYSGRYLNL TVSEDKERLD HGKLRKPCYC GAKSCTAFLP F

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human SETMAR (NP_006506.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SETMAR

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Andere Bezeichnung: SETMAR (SETMAR Produkte)

Hintergrund: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.,SETMAR,METNASE,Mar1,Epigenetics & Nuclear Signaling,SETMAR

Molekulargewicht: 40 kDa/62 kDa/78 kDa

Gen-ID: 6419

UniProt: Q53H47

Pathways: Positive Regulation of Response to DNA Damage Stimulus