SFTPB Antikörper (AA 94-393)

Produktnummer ABIN6147687

Produktdetails anti-SFTPB Antikörper

Target: SFTPB (Surfactant Protein B (SFTPB))

Bindungsspezifität: AA 94-393

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFTPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAKEAIFQDT MRKFLEQECN VLPLKLLMPQ CNQVLDDYFP LVIDYFQNQT DSNGICMHLG LCKSRQPEPE QEPGMSDPLP KPLRDPLPDP LLDKLVLPVL PGALQARPGP HTQDLSEQQF PIPLPYCWLC RALIKRIQAM IPKGALAVAV AQVCRVVPLV AGGICQCLAE RYSVILLDTL LGRMLPQLVC RLVLRCSMDD SAGPRSPTGE WLPRDSECHL CMSVTTQAGN SSEQAIPQAM LQACVGSWLD REKCKQFVEQ HTPQLLTLVP RGWDAHTTCQ ALGVCGTMSS PLQCIHSPDL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 94-393 of human SFTPB (NP_000533.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SFTPB

Target: SFTPB (Surfactant Protein B (SFTPB))

Andere Bezeichnung: SFTPB (SFTPB Produkte)

Hintergrund: This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.,SFTPB,PSP-B,SFTB3,SFTP3,SMDP1,SP-B,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,SFTPB

Molekulargewicht: 42 kDa

Gen-ID: 6439

UniProt: P07988