SKIL Antikörper (AA 420-684)
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- Target Alle SKIL Antikörper anzeigen
- SKIL (SKI-Like Oncogene (SKIL))
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Bindungsspezifität
- AA 420-684
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SKIL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SQSKELTKTE ASKSISRQSE KAHSSGKLQK TVSYPDVSLE EQEKMDLKTS RELCSRLDAS ISNNSTSKRK SESATCNLVR DINKVGIGLV AAASSPLLVK DVICEDDKGK IMEEVMRTYL KQQEKLNLIL QKKQQLQMEV KMLSSSKSMK ELTEEQQNLQ KELESLQNEH AQRMEEFYVE QKDLEKKLEQ IMKQKCTCDS NLEKDKEAEY AGQLAELRQR LDHAEADRQE LQDELRQERE ARQKLEMMIK ELKLQILKSS KTAKE
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 420-684 of human SKIL (NP_001234937.1).
- Isotyp
- IgG
- Top Product
- Discover our top product SKIL Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SKIL (SKI-Like Oncogene (SKIL))
- Andere Bezeichnung
- SKIL (SKIL Produkte)
- Hintergrund
- The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.,SKIL,SNO,SnoA,SnoI,SnoN,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Target gene,SKIL
- Molekulargewicht
- 44 kDa/46 kDa/71 kDa/74 kDa/76 kDa
- Gen-ID
- 6498
- UniProt
- P12757
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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