SKIL Antikörper (AA 420-684)

Produktnummer ABIN6147811

Produktdetails anti-SKIL Antikörper

Target: SKIL (SKI-Like Oncogene (SKIL))

Bindungsspezifität: AA 420-684

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SQSKELTKTE ASKSISRQSE KAHSSGKLQK TVSYPDVSLE EQEKMDLKTS RELCSRLDAS ISNNSTSKRK SESATCNLVR DINKVGIGLV AAASSPLLVK DVICEDDKGK IMEEVMRTYL KQQEKLNLIL QKKQQLQMEV KMLSSSKSMK ELTEEQQNLQ KELESLQNEH AQRMEEFYVE QKDLEKKLEQ IMKQKCTCDS NLEKDKEAEY AGQLAELRQR LDHAEADRQE LQDELRQERE ARQKLEMMIK ELKLQILKSS KTAKE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 420-684 of human SKIL (NP_001234937.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SKIL

Target: SKIL (SKI-Like Oncogene (SKIL))

Andere Bezeichnung: SKIL (SKIL Produkte)

Synonyme: SNO antikoerper, SnoA antikoerper, SnoI antikoerper, SnoN antikoerper, Skir antikoerper, Sno antikoerper, SKIL antikoerper, DKFZp459L122 antikoerper, sno antikoerper, zgc:193698 antikoerper, SKI like proto-oncogene antikoerper, SKI-like proto-oncogene antikoerper, ski-like protein antikoerper, SKI-like antikoerper, SKI-like proto-oncogene b antikoerper, SKIL antikoerper, Skil antikoerper, LOC100010058 antikoerper, skil antikoerper, skilb antikoerper

Hintergrund: The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.,SKIL,SNO,SnoA,SnoI,SnoN,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Target gene,SKIL

Molekulargewicht: 44 kDa/46 kDa/71 kDa/74 kDa/76 kDa

Gen-ID: 6498

UniProt: P12757

Pathways: Positive Regulation of Response to DNA Damage Stimulus