CD4 Antikörper (PE)
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- Target Alle CD4 Antikörper anzeigen
- CD4
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD4 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- This antibody reacts with an extracellular epitope of mouse CD4 transmembrane glycoprotein (55 kDa).
- Kreuzreaktivität (Details)
- Species reactivity (tested):Mouse
- Immunogen
- Mouse CTL clone V4 cells
- Klon
- GK1-5
- Isotyp
- IgG2b
- Top Product
- Discover our top product CD4 Primärantikörper
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anti-CD4 (CD4) (AA 385-457) antibody
CD4 Reaktivität: Human, Maus, Ratte, Huhn, Schwein FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) antibodyCD4 Reaktivität: Human, Maus, Ratte, Huhn, Affe, Hund, Schwein, Cat, Rind (Kuh), Kaninchen, Schaf, Meerschweinchen, Ziege, Pferd, Avian, Esel, Hamster WB Wirt: Ziege Polyclonal unconjugated
anti-CD4 (CD4) (AA 231-330) antibodyCD4 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) (N-Term) antibodyCD4 Reaktivität: Human FACS, WB, CyTOF Wirt: Maus Monoclonal MEM-241 unconjugated
anti-CD4 (CD4) (AA 300-400) antibodyCD4 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) antibodyCD4 Reaktivität: Maus FACS, IP, IHC (fro), ICC, Func Wirt: Ratte Monoclonal GK1-5 unconjugated
anti-CD4 (CD4) (N-Term) antibody (FITC)CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 FITC
anti-CD4 (CD4) (AA 301-400) antibodyCD4 Reaktivität: Human, Maus, Ratte FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) (N-Term) antibody (PE)CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 PE
anti-CD4 (CD4) antibody (PE)CD4 Reaktivität: Ratte FACS Wirt: Maus Monoclonal OX-35 PE
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS, approx. pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- DO NOT FREEZE! This product is photosensitive and should be protected from light.
- Lagerung
- 4 °C
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- Target
- CD4
- Andere Bezeichnung
- CD4 (CD4 Produkte)
- Hintergrund
- CD4 is a single chain transmembrane glycoprotein of immunoglobulin supergene family. In its extracellular region there are 4 immunoglobulin-like domains (1 Ig-like V-type and 3 Ig-like C2-type). The intracellular region of CD4 associates with p56Lck, a Src-like protein tyrosine kinase. It was described that CD4 segregates into specific detergent-resistant T-cell membrane microdomains. CD4 binds to MHC class II molecules (by CDR2-like region in CD4 domain 1), HIV envelope protein gp120 (by CDR2-like region in CD4 domain 1) and other ligands, such as IL-16 (by to CD4 domain 3) or L-selectin. CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molecules) and HIV infection. CD4 regulates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction. Defects in antigen presentation (MHC class II) cause dysfunction of CD4+ T-cells and their almost complete absence in patients blood, tissue and organs (SCID immunodeficiency).Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
- Gen-ID
- 12504, 10090
- UniProt
- P06332
- Pathways
- T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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