CD34 Antikörper
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- Target Alle CD34 Antikörper anzeigen
- CD34
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Reaktivität
- Human, Primate
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD34 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Spezifität
- This antibody reacts with Class II epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. This antibody has been also used as an endothelial marker.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Non-Human Primates, negative on Rat, Bovine, Sheep, Canine (Dog)
- Aufreinigung
- Protein-A affinity chromatography
- Reinheit
- > 95 % pure by SDS-PAGE
- Immunogen
- Human endothelial vesicles
- Klon
- QBEnd-10
- Isotyp
- IgG1
- Top Product
- Discover our top product CD34 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μm filter sterilized
- Konservierungsmittel
- Azide free
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- CD34
- Andere Bezeichnung
- CD34 (CD34 Produkte)
- Synonyme
- AU040960 antikoerper, CD34 molecule antikoerper, CD34 antigen antikoerper, CD34 antikoerper, Cd34 antikoerper
- Hintergrund
- CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.Synonyms: Hematopoietic progenitor cell antigen CD34, Hematopoietic progenitor cell marker
- Gen-ID
- 947
- NCBI Accession
- NP_001020280
- UniProt
- P28906
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