SPTAN1 Antikörper (AA 950-1130)

Produktnummer ABIN6148403

Produktdetails anti-SPTAN1 Antikörper

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Bindungsspezifität: AA 950-1130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPTAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: REQAQSCRQQ VAPTDDETGK ELVLALYDYQ EKSPREVTMK KGDILTLLNS TNKDWWKVEV NDRQGFVPAA YVKKLDPAQS ASRENLLEEQ GSIALRQEQI DNQTRITKEA GSVSLRMKQV EELYHSLLEL GEKRKGMLEK SCKKFMLFRE ANELQQWINE KEAALTSEEV GADLEQVEVL Q

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 950-1130 of human Alpha Fodrin (NP_001123910.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-SPTAN1 Antikörper (ABIN6148403)

Meng, Zhang, Shi, Zhang, Yuan: "Inhibition of interleukin-6 abolishes the promoting effects of pair housing on post-stroke neurogenesis." in: Neuroscience, Vol. 307, pp. 160-70, (2016) (PubMed).

Details zu SPTAN1

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Andere Bezeichnung: SPTAN1 (SPTAN1 Produkte)

Synonyme: im:7157190 antikoerper, wu:fa20e05 antikoerper, wu:fb33g08 antikoerper, wu:fk32a10 antikoerper, zgc:112229 antikoerper, 2610027H02Rik antikoerper, Spna-2 antikoerper, Spna2 antikoerper, EIEE5 antikoerper, NEAS antikoerper, SPTA2 antikoerper, A2a antikoerper, IPF antikoerper, SPECA antikoerper, spectrin alpha, non-erythrocytic 1 antikoerper, spectrin, alpha, non-erythrocytic 1 antikoerper, SPTAN1 antikoerper, sptan1 antikoerper, Sptan1 antikoerper

Hintergrund: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.,SPTAN1,EIEE5,NEAS,SPTA2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,Death Receptor Signaling Pathway,SPTAN1

Molekulargewicht: 282 kDa/284 kDa/285 kDa

Gen-ID: 6709

UniProt: Q13813

Pathways: Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization