SQSTM1 Antikörper (AA 1-440)
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- Target Alle SQSTM1 Antikörper anzeigen
- SQSTM1 (Sequestosome 1 (SQSTM1))
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Bindungsspezifität
- AA 1-440
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SQSTM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Sequenz
- MAMSYVKDDI FRIYIKEKKE CRRDHRPPCA QEAPRNMVHP NVICDGCNGP VVGTRYKCSV CPDYDLCSVC EGKGLHRGHT KLAFPSPFGH LSEGFSHSRW LRKVKHGHFG WPGWEMGPPG NWSPRPPRAG EARPGPTAES ASGPSEDPSV NFLKNVGESV AAALSPLGIE VDIDVEHGGK RSRLTPVSPE SSSTEEKSSS QPSSCCSDPS KPGGNVEGAT QSLAEQMRKI ALESEGRPEE QMESDNCSGG DDDWTHLSSK EVDPSTGELQ SLQMPESEGP SSLDPSQEGP TGLKEAALYP HLPPEADPRL IESLSQMLSM GFSDEGGWLT RLLQTKNYDI GAALDTIQYS KHPPPL
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-440 of human SQSTM1/p62 (NP_001135770.1).
- Isotyp
- IgG
- Top Product
- Discover our top product SQSTM1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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Regulation of SREBP-2 intracellular trafficking improves impaired autophagic flux and alleviates endoplasmic reticulum stress in NAFLD." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1862, Issue 3, pp. 337-350, (2017) (PubMed).
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Regulation of SREBP-2 intracellular trafficking improves impaired autophagic flux and alleviates endoplasmic reticulum stress in NAFLD." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1862, Issue 3, pp. 337-350, (2017) (PubMed).
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- Target
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Andere Bezeichnung
- SQSTM1 (SQSTM1 Produkte)
- Synonyme
- SQSTM1 antikoerper, sqstm1 antikoerper, MGC79491 antikoerper, A170 antikoerper, OSIL antikoerper, PDB3 antikoerper, ZIP3 antikoerper, p60 antikoerper, p62 antikoerper, p62B antikoerper, OSF-6 antikoerper, Osi antikoerper, STAP antikoerper, ZIP antikoerper, sb:cb621 antikoerper, zgc:85784 antikoerper, sequestosome 1 antikoerper, sequestosome 1 L homeolog antikoerper, SQSTM1 antikoerper, sqstm1 antikoerper, Sqstm1 antikoerper, sqstm1.L antikoerper
- Hintergrund
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.,SQSTM1,A170,DMRV,FTDALS3,NADGP,OSIL,PDB3,ZIP3,p60,p62,p62B,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Cardiovascular,Heart,Mitochondrial Control of Autophagy,SQSTM1
- Molekulargewicht
- 38 kDa/47 kDa
- Gen-ID
- 8878
- UniProt
- Q13501
- Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
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