SSX4 Antikörper (AA 70-188)

Produktnummer ABIN6148508

Produktdetails anti-SSX4 Antikörper

Target: SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

Bindungsspezifität: AA 70-188

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FMRSKRAADF HGNDFGNDRN HRNQVERPQM TFGSLQRIFP KIMPKKPAEE ENGLKEVPEA SGPQNDGKQL CPPGNPSTLE KINKTSGPKR GKHAWTHRLR ERKQLVVYEE ISDPEEDDE

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-188 of human SSX4 (NP_005627.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SSX4

Target: SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

Andere Bezeichnung: SSX4 (SSX4 Produkte)

Synonyme: CT5.4 antikoerper, SSX family member 4 antikoerper, SSX4 antikoerper

Hintergrund: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.,SSX4,CT5.4,SSX4

Molekulargewicht: 17 kDa/21 kDa

Gen-ID: 6759

UniProt: O60224