STK4 Antikörper (AA 303-487)

Produktnummer ABIN6148620

Produktdetails anti-STK4 Antikörper

Target: STK4 (serine/threonine Kinase 4 (STK4))

Bindungsspezifität: AA 303-487

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Sequenz: KRQESQQREV DQDDEENSEE DEMDSGTMVR AVGDEMGTVR VASTMTDGAN TMIEHDDTLP SQLGTMVINA EDEEEEGTMK RRDETMQPAK PSFLEYFEQK EKENQINSFG KSVPGPLKNS SDWKIPQDGD YEFLKSWTVE DLQKRLLALD PMMEQEIEEI RQKYQSKRQP ILDAIEAKKR RQQNF

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 303-487 of human MST1/STK4 (NP_006273.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-STK4 Antikörper (ABIN6148620)

Zhang, Xu, Xu, Wei, Xu: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." in: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).

Details zu STK4

Target: STK4 (serine/threonine Kinase 4 (STK4))

Andere Bezeichnung: STK4 (STK4 Produkte)

Hintergrund: The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.,KRS2,MST1,YSK3,STK4,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Hippo Signaling Pathway,Cardiovascular,Heart,Hypertrophy,STK4

Molekulargewicht: 52 kDa/55 kDa

Gen-ID: 6789

UniProt: Q13043

Pathways: Tube Formation